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You are here:Home » Antibodies » Abs to Enzymes, Phospholipase » Anti -Chak, CT (TRPM7, Transient Receptor Potential Cation Channel Subfamily M Member 7, Channel-kinase 1, Long Transient Receptor Potential Channel 7, LTrpC-7, LTrpC7, Transient Receptor Potential-phospholipase C-interacting Kinase, TRP-PLIK)

Anti -Chak, CT (TRPM7, Transient Receptor Potential Cation Channel Subfamily M Member 7,
Channel-kinase 1, Long Transient Receptor Potential Channel 7, LTrpC-7, LTrpC7, Transient
Receptor Potential-phospholipase C-interacting Kinase, TRP-PLIK)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IH IC
Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).
Catalog #C3445-26F
ApplicationsSuitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1-10ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Immunocytochemistry: 0.1-1ug/ml
Immunoprecipitation: 1-10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoS74-25
HostMouse
SourceMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH7.4, 0.09% sodium azide, 50% glycerol.
PurityPurified by Protein G affinity chromatography.
ImmunogenFusion protein aa817-1863 of mouse TrpM7 at C- terminus.
SpecificityRecognizes mouse TRPM7 at ~220kD. Species sequence homology: Human, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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