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Anti -Chak, CT (TRPM7, Transient Receptor Potential Cation Channel Subfamily M Member 7, Channel-kinase 1, Long Transient Receptor Potential Channel 7, LTrpC-7, LTrpC7, Transient Receptor Potential-phospholipase C-interacting Kinase, TRP-PLIK)
Anti -Chak, CT (TRPM7, Transient Receptor Potential Cation Channel Subfamily M Member 7,
Channel-kinase 1, Long Transient Receptor Potential Channel 7, LTrpC-7, LTrpC7, Transient
Receptor Potential-phospholipase C-interacting Kinase, TRP-PLIK)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IP IH IC |
|
| Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). | | | Catalog # | C3445-26F | | Applications | Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1-10ug/ml | | Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml | | Immunocytochemistry: 0.1-1ug/ml | | Immunoprecipitation: 1-10ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | S74-25 | | Host | Mouse | | Source | Mouse | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH7.4, 0.09% sodium azide, 50% glycerol. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Fusion protein aa817-1863 of mouse TrpM7 at C- terminus. | | Specificity | Recognizes mouse TRPM7 at ~220kD. Species sequence homology: Human, rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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