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Anti -Chapsyn 110 (PSD93, Discs Large Homolog 2, DLG2, Channel-associated Protein of SynapsesChapsyn 110 (PSD93, Discs Large Homolog 2, DLG2, Channel-associated Protein of Synapses)
Anti -Chapsyn 110 (PSD93, Discs Large Homolog 2, DLG2, Channel-associated Protein of
SynapsesChapsyn 110 (PSD93, Discs Large Homolog 2, DLG2, Channel-associated Protein of
Synapses)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IP IH |
|
| Chapsyn-110, is a part of the membrane-associated putative guanylate kinase (MAGUK) family. It binds directly to the NMDA receptor, and Shaker K+ channel subunits, and is 70-80% identical to PSD-95/SAP90 and SAP97 (1). It associated tightly with the postsynaptic density I brain, and mediates the clustering of both NMDA recpetors and K+ channels in heterologous cells. The | | | encoded protein forms a heterodimer with PSD-95 that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins (1, 2). | | | Catalog # | C3550-05 | | Applications | Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot:1-10ug/ml | | Immunohistochemistry:0.1-1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 10F694 | | Host | Mouse | | Source | Rat | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH7.4, 50% glycerol and 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Fusion protein aa 1-852 of rat Chapsyn-110 (accession number Q63622). | | Specificity | Recognizes rat Chapsyn-110. Species Crossreactivity: human (weak). No cross-reactivity against other. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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