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You are here:Home » Antibodies » Abs to Binding Proteins » Anti -CHD3 (Chromodomain Helicase DNA Binding Protein 3, CHD-3, ATP-dependent Helicase CHD3, hZFH, Mi-2a, Mi-2 alpha, Mi-2 Autoantigen 240kD Protein, ZFH, Zinc-finger Helicase (Snf2-like)) (Azide Free)

Anti -CHD3 (Chromodomain Helicase DNA Binding Protein 3, CHD-3, ATP-dependent Helicase
CHD3, hZFH, Mi-2a, Mi-2 alpha, Mi-2 Autoantigen 240kD Protein, ZFH, Zinc-finger Helicase
(Snf2-like)) (Azide Free)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Catalog #C3875-50D
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 0.1-10ug/ml
ELISA: 1ug/ml-3ng/ml
Western Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10B2215
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant protein corresponding to a portion of amino acids within aa1654-1742 of human CHD3.
SpecificityRecognizes human CHD3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names2600010P09Rik, AF020312, MGC40857, Prp9-1


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