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You are here:Home » Antibodies » Abs to Infectious Disease Cholera » Anti -Cholera Toxin, alpha, Vibrio cholerae

Anti -Cholera Toxin, alpha, Vibrio cholerae

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E
The cholera holotoxin consists of a pentameric ring of Beta subunits whose central pore is occupied by the Alpha subunit. The Alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The Alpha subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.
Catalog #C4275-35H
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Recommended Secondary AntibodiesI1905-18D: IgM (X-Adsorbed) (FITC) Pab GtxMo
I1905-28A: IgM (X-Adsorbed) (HRP) Pab GtxMo
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgM
Clone No3j3
HostMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenVibrio cholerae extract
SpecificityRecognizes the alpha chain of the V. cholerae toxin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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