Anti -Cholera Toxin, beta (Beta Subunit Cholera Toxin, Cholera Enterotoxin beta Chain,
Cholera Enterotoxin B Chain, Cholera Enterotoxin gamma Chain, Cholera Enterotoxin Subunit
B, Cholera Toxin B Protein, Choleragenoid, CTX B, CTXB, CTX-B, TOXB, VC1456)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Highly Purified |
E IP |
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| The Beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin Alpha subunit into cells. The holotoxin consists of a pentameric ring of Beta subunits whose central pore is occupied by the Alpha subunit. The Alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The Alpha subunit (and Cholera toxin) activate the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. | | | Catalog # | C4275-35M | | Applications | Suitable for use in ELISA and Immunoprecipitation. Other applications not tested. | | Recommended Dilutions | Optimal dilutions to be determined by the researcher. | | Titer | >1:1000 by ELISA | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Concentration | ~4-5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. No stabilizing proteins have been added. | | Purity | Purified IgG fraction to a purity of > 95%. | | Immunogen | Purified Choleragenoid | | Specificity | Recognizes the Beta subunit of Cholera toxin. Cross reacts with E.coli heat liable toxin. Immunoprecipitates toxin in gel techniques. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Cholera Toxin, beta (Beta Subunit Cholera Toxin, Cholera Enterotoxin beta Chain, Cholera Enterotoxin B Chain, Cholera Enterotoxin gamma Chain, Cholera Enterotoxin Subunit B, Cholera Toxin B Protein, Choleragenoid, CTX B, CTXB, CTX-B, TOXB, VC1456) |
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