Anti -Cholera Toxin, beta (Beta Subunit Cholera Toxin, Cholera Enterotoxin beta Chain,
Cholera Enterotoxin B Chain, Cholera Enterotoxin gamma Chain, Cholera Enterotoxin Subunit
B, Cholera Toxin B Protein, Choleragenoid, CTX B, CTXB, CTX-B, TOXB, VC1456)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IH IF |
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| The Beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin Alpha subunit into cells. The holotoxin consists of a pentameric ring of Beta subunits whose central pore is occupied by the Alpha subunit. The Alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The Alpha subunit (and Cholera toxin) activate the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. | | | Catalog # | C4275-35Y | | Applications | Suitable for use in Immunofluorescence, Immunohistochemistry, ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Immunofluorescence: 1:10-1:50 | | ELISA: 1:20-1:200 | | Western Blot: 1:10-1:50 | | Immunohistochemistry: 1:10-1:50 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 12K223 | | Host | Mouse | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Purified native B subunit. | | Specificity | Recognizes the B subunit of cholera toxin. Reacts with intact toxin. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Cholera Toxin, beta (Beta Subunit Cholera Toxin, Cholera Enterotoxin beta Chain, Cholera Enterotoxin B Chain, Cholera Enterotoxin gamma Chain, Cholera Enterotoxin Subunit B, Cholera Toxin B Protein, Choleragenoid, CTX B, CTXB, CTX-B, TOXB, VC1456) |
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