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You are here:Home » Biochemicals » Biochem-Antibiotics » Chloramphenicol succinate sodium salt

Chloramphenicol succinate sodium salt


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Chloramphenicol is a chlorine-containing antibiotic produced by Streptomyces venezuelae. It has a wide spectrum of activity against gram-positive and gram-negative cocci and bacilli (including anaerobes), Rickettsia, Mycoplasma, and Chlamydia. It inhibits prokaryotic protein synthesis by attaching to the 50S ribosomal subunit. This inhibits peptidyltransferase, thereby preventing the formation of peptide bonds. It also inhibits protein synthesis in mitochondria which accounts for its toxic effects that cause aplastic anemia. Chloramphenicol has other adverse effects such as bone marrow depression, and gray baby syndrome. Itís use is limited to serious infections such as those where resistance to other antibiotics occurs. It is still widely used in the treatment of typhoid fever, meningitis and eye infections.
Catalog #C4350-07
Appearance White to light-yellow powder
Solubility (H2O) Clear to very slightly hazy faint yellow solution at 50mg/ml. Soluble in water and alcohol.
Purity 80% (HPLC)
CAS Number982-57-0
Molecular FormulaC15H15Cl2N2O8Na
Molecular Weight445.18
Purity80% (HPLC)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesChloramphenicol alpha-succinate

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