Anti -CHMP5 (Charged Multivesicular Body Protein 5, Chromatin-modifying Protein 5, SNF7
Domain-containing Protein 2, Vacuolar Protein Sorting-associated Protein 60, Vps60,
hVps60, C9orf83, SNF7DC2, CGI-34, HSPC177, PNAS-2, PNAS-114)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
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| CHMP5 is a component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In case of infection, the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargoes of viral proteins. | | | Catalog # | C5039-02C | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:8000 | | Western Blot: 1-3ug/ml, observed in lysates of K562 on ~28kD bands | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to C-NKDGVLVDEFGLPQ, from human CHMP5, at C-terminal (NP_057494.3). | | Specificity | Recognizes human CHMP5. Species sequence homology: Bovine, mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -CHMP5 (Charged Multivesicular Body Protein 5, Chromatin-modifying Protein 5, SNF7 Domain-containing Protein 2, Vacuolar Protein Sorting-associated Protein 60, Vps60, hVps60, C9orf83, SNF7DC2, CGI-34, HSPC177, PNAS-2, PNAS-114) |
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