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You are here:Home » Antibodies » Abs to Enzymes, Acetyltransferase » Anti -Choline Acetyltransferase (Choline O-acetyltransferase, CHOACTase, ChAT, Choline Acetylase, CMS1A, CMS1A2)

Anti -Choline Acetyltransferase (Choline O-acetyltransferase, CHOACTase, ChAT, Choline
Acetylase, CMS1A, CMS1A2)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
Choline Acetyltransferase (ChAT) is an enzyme that catalyzes the synthesis of acetylcholine from choline and acetyl coenzyme A, and is found in cholinergic neurons in the CNS. Interestingly, specific loss of cholinergic neurons has been reported in the basal forebrain in Lewy Body Dementia and Alzheimer’s disease. It does not react with axons in the insular cortex or the internal capsule, non-cholinergic structures, endothelial cells or microglia.
Catalog #C5057-09C
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 1:25-1:50 for 1 hr. at RT
Optimal dilutions to be determined by the researcher.
Positive Control
Basal ganglia (cytoplasmic staining pattern)
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No38B12
HostMouse
ConcentrationNot determined
FormSupplied as a lyophilized powder in 15mM sodium azide. Reconstitute with 1ml dH2O.
PuritySupernatant
ImmunogenRecombinant protein corresponding to the C-terminal portion of the human ChAT molecule.
SpecificityRecognizes Choline Acetyltransferase. Species Crossreactivity: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAcetyl CoA:choline O-acetyltransferase, Choline O Acetyltransferase, EC=2.3.1.6


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