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You are here:Home » Antibodies » Abs to Receptors, Cholinergic » Anti -Cholinergic Receptor, Nicotinic, alpha 5 (CHRNA5)

Anti -Cholinergic Receptor, Nicotinic, alpha 5 (CHRNA5)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Nicotinic acetylcholine receptors, also known as nAChRs, belong to a family of proteins called ligand gated ion channels and are widely expressed throughout the nervous system. nAChRs are made up of 5 subunits (two alpha and three beta). Nicotinic Acetylcholine Receptor a5 has an ax ay beta combination. In the CNS, the a5 subunit is widely expressed in the CA1 area of the hippocampus which affects learning, memory, attention, anxiety, and potentially drug seeking behaviors.
Catalog #C5062-74B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500
Optimal dilutions to be determined by the researcher.
Positive ControlRat e16 brain lysate
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceRat
Concentration~0.5mg/ml
FormSupplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide selected from residues of nicotinic acetylcholine receptor a5 (KLH). Epitope: Extracellular domain.
SpecificityRecognizes rat Nicotinic Acetylcholine Receptor a5.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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