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CHP, aa1-195, Recombinant, Human (Calcium Binding Protein P22, Calcineurin B Homolog, Calcineurin Homologous Protein, Calcium-binding Protein CHP)
CHP, aa1-195, Recombinant, Human (Calcium Binding Protein P22, Calcineurin B Homolog,
Calcineurin Homologous Protein, Calcium-binding Protein CHP)
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| CHP (Calcium-binding protein P22) is a phosphoprotein that binds to the sodium-hydrogen exchangers (NHEs). This protein serves as an essential cofactor which supports the physiological activity of NHE family members. It has protein sequence similarity to calcineurin B and it is also known to be an endogenous inhibitor of calcineurin activity. | | | Catalog # | C5068-65 | | Source | Recombinant corresponding to aa1-195 of human CHP 6x his tagged, expressed in E.coli. | | AA Sequences | MGSSHHHHHH SSGLVPRGSH MMGSRASTLL RDEELEEIKK ETGFSHSQIT RLYSRFTSLD KGENGTLSRE DFQRIPELAI NPLGDRIINA FFPEGEDQVN FRGFMRTLAH FRPIEDNEKS KDVNGPEPLN SRSNKLHFAF RLYDLDKDEK ISRDELLQVL RMMVGVNISD EQLGSIADRT IQEADQDGDS AISFTEFVKV LEKVDVEQKM SIRFLH | | Molecular Weight | 24.7kD (216aa), confirmed by MALDI-TOF | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 24.7kD | | Source | E.coli | | Purity | ~95% (SDS-PAGE). | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 10% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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