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You are here:Home » Molecular Biology » MB-Hormones, Steroids » Chorionic Gonadotropin, Human, alpha (hCGa)

Chorionic Gonadotropin, Human, alpha (hCGa)

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Specifications

Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the a-and b-subunits. The a-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma.
Catalog #C5069-52A
SourceHuman Chorionic Gonadotropin alpha subunit (hCG-a), from urine.
Molecular Weight~14.5kD
Activity1mg protein/mg powder (OD280nm).
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~14.5kD
SourceHuman urine
Purity~98% (SDS-PAGE)
ConcentrationNot determined
FormSupplied as a lyophilized from 50mM ammonium bicarbonate. Reconstitute using neutral pH buffer.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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