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You are here:Home » Molecular Biology » MB-Hormones, Steroids » Chorionic Gonadotropin, Human, beta (hCGb)

Chorionic Gonadotropin, Human, beta (hCGb)


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Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera and rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the a-and b-subunits. The a-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma.
Catalog #C5069-86
ApplicationSuitable for antigenic applications in immunological protocols.
Recommended DilutionsOptimal dilutions to be determined by researcher.
Biological ActivitySpecific Activity = >1,000 IU/mg (WHO 1st IRP (75/551)
Storage and StabilityLyophilized powder may be stored at -20°C. Powder is stable for 12 months at -20°C. Aliquot reconstituted product and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceHuman pregnancy urine
Purity98% by SDS-PAGE. Purified by HPLC. Contaminants
FormSupplied as a lyophilized powder from 50mM ammonium bicarbonate. Reconstitute with PBS, pH 7.5, at 1-2mg/ml.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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