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Chorionic Gonadotropin, Human, beta (hCGb)
Chorionic Gonadotropin, Human, beta (hCGb)
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| Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the a-and b-subunits. The a-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma. | | | Catalog # | C5069-89A | | Source | Human Chorionic Gonadotropin beta subunit (hCG-b), from urine. | | Molecular Weight | ~22kD | | Activity | 1mg protein/mg powder | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | ~22kD | | Source | Human urine | | Purity | ~98% (SDS-PAGE) | | Concentration | Not determined | | Form | Supplied as a lyophilized from 50mM ammonium bicarbonate. Reconstitute using neutral pH buffer. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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