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You are here:Home » Antibodies » Abs to Chromogranin » Anti -Chromogranin A (CgA, CHGA, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, SP-I)

Anti -Chromogranin A (CgA, CHGA, Parathyroid Secretory Protein 1, Pituitary Secretory
Protein I, SP-I)

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Specifications

Clone Host Grade Applications
Polyclonal Sheep Purified E IH
Chromogranin A is a secreted peptide that inhibits glucose-induced insulin release. Chromogranin A is an activator of microglia (Taupenaut et al. 1996) and is notably upregulated and prominantly expressed in the senile plaques associated with Alzheimer's disease (Yasuhara et al. 1994).
Catalog #C5069-96P
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Paraffin): 1:25-1:100. Requires protein digestion pre-treatment of paraffin sections. Pronase is recommended for this purpose
Optimal dilutions to be determined by the researcher.
IHC Positive ControlHuman pancreas
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostSheep
SourceHuman
Concentration~5mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1-15 LPVNSPMNKGDTEVM of native human Chromogranin A, conjugated to KLH.
Species Sequence HomologyBovine, chimpanzee, canine, equine, porcine, mouse, rat
SpecificityRecognizes human Chromogranin A.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesChromogranin A (Parathyroid Secretory Protein 1), Chromogranin A Precursor


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