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You are here:Home » Antibodies » Abs to Chromogranin » Anti -Chromogranin A (CGA, CHG A, Pancreastatin, Parathyroid secretory protein 1, Pituitary secretory protein I, Vasostatin, SPI)

Anti -Chromogranin A (CGA, CHG A, Pancreastatin, Parathyroid secretory protein 1,
Pituitary secretory protein I, Vasostatin, SPI)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.
Catalog #C5069-97D
ApplicationsSuitable for use in ELISA (peptide) and Western Blot. Other applications not tested.
Recommended DilutionELISA (peptide): 1:4000 (detection limit).
Western Blot: 0.1-0.3ug/ml. ~ 50kD band observed in human kidney lysates (calculated MW of 50.7kD according to NP_001266.1).
Optimal dilutions to be determined by the researcher.
Positive Control Human Kidney lysate
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH7.3, containing 0.5% BSA and 0.02% sodium azide
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide, C-QGAKERAHQQKKH, representing the internal region of the human protein according to NP_001266.1
SpecificityRecognizes human Chromogranin A
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCGA, CHG A, Chromogranin A parathyroid secretory protein 1, Pancreastatin, Parathyroid secretory protein 1, Pituitary secretory protein I, Vasostatin, SPI


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