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You are here:Home » Biochemicals » Biochem-Antibiotics » Chromomycin A3

Chromomycin A3


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Chromomycin A3 is the major component of the chromomycin complex of the aureolic acid class, isolated from several Streptomyces species and first reported in 1960. Chromomycin A3 exhibits a broad biological profile as an antibacterial, antifungal and antitumor agent. It binds reversibly to GC-specific DNA ligand in the minor groove which inhibits transcription, DNA gyrase and topoisomerase II. The intense UV spectrum and strong fluorescence makes chromomycin a useful stain for DNA.
Catalog #C5180
SourceChromomycin A3 from Stretomyces griseus.
Molecular Weight~1183.3
SolubilitySoluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number7059-24-7
Molecular FormulaC57H82O26
Molecular Weight~1183.3
Purity~98% (HPLC)
ConcentrationNot determined
FormSupplied as a yellow powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.

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