Anti -CKTSF1B1 (Gremlin-1, Cell Proliferation-inducing Gene 2 Protein, Cysteine Knot
Superfamily 1, BMP Antagonist 1, DAN Domain Family Member 2, Down-regulated in
Mos-transformed Cells Protein, Increased in High Glucose Protein 2, IHG-2, GREM1, DAND2,
DRM, PIG
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
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| In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13--> q15. DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine and colon. It has been suggested that down-regulation of DRM is associated with tumor progression, and support the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis. | | | Catalog # | C5818-06C | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 2.5-10ug/ml | | Immunohistochemistry: Frozen | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human colon cancer tissue | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aQPGSRNRGRGQGRGTA (52-67) of human CKTSF1B1. (Genbank accession no. NM_013372) | | Specificity | Recognizes human CKTSF1B1. Species Crossreactivity: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -CKTSF1B1 (Gremlin-1, Cell Proliferation-inducing Gene 2 Protein, Cysteine Knot Superfamily 1, BMP Antagonist 1, DAN Domain Family Member 2, Down-regulated in Mos-transformed Cells Protein, Increased in High Glucose Protein 2, IHG-2, GREM1, DAND2, DRM, PIG |
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