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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -CKTSF1B1 (Gremlin-1, Cell Proliferation-inducing Gene 2 Protein, Cysteine Knot Superfamily 1, BMP Antagonist 1, DAN Domain Family Member 2, Down-regulated in Mos-transformed Cells Protein, Increased in High Glucose Protein 2, IHG-2, GREM1, DAND2, DRM, PIG

Anti -CKTSF1B1 (Gremlin-1, Cell Proliferation-inducing Gene 2 Protein, Cysteine Knot
Superfamily 1, BMP Antagonist 1, DAN Domain Family Member 2, Down-regulated in
Mos-transformed Cells Protein, Increased in High Glucose Protein 2, IHG-2, GREM1, DAND2,
DRM, PIG

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13--> q15. DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine and colon. It has been suggested that down-regulation of DRM is associated with tumor progression, and support the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.
Catalog #C5818-06C
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 2.5-10ug/ml
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.
Positive ControlHuman colon cancer tissue
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aQPGSRNRGRGQGRGTA (52-67) of human CKTSF1B1. (Genbank accession no. NM_013372)
SpecificityRecognizes human CKTSF1B1. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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