Anti -CLARA CELL PROTEIN (CC10, CC16, CCPBP, CCSP, Clara cell phospholipid-binding protein, Clara cells 10kD secretory protein, Secretoglobin family 1A member 1, UGB, UP1, Urinary protein 1, Urine Protein 1, Uteroglobin Precursor)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IH |
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| Clara cell protein or urinary protein 1 is a homodimeric protein of 16kD and is secreted predominantly by Clara cells in terminal bronchioles and from puberty on in the male urogenital tract. CC16 is formed by two chains, each with a molecular weight of 7.9kD. CC16 occurs in very high concentrations in respiratory tract derived fluids such as sputum or bronchoalveolar lavage fluid. CC16 occurs also in urogenital secretions, such as amniotic fluid, urine and semen. The protein difusses passively into serum. CC16 behaves like an anti-cytokine by downregulating the | | | production of IFN-gamma, IL-1 and TNF-alpha by stimulated leukocytes. Besides this, CC16 reduces the antiviral activity and the augmentation of phagocytosis induced by IFN-gamma. | | | Catalog # | C5828-01B | | Applications | Suitable for use in Immunoassays, Western Blot, and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Western Blot: 1:50 | | Immunohistochemistry: 1:50 | | Optimal dilution to be determined by researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 9G168 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide. | | Purity | Purified | | Immunogen | Human Clara Cell Protein. | | Specificity | Recognizes the anti-inflammatory mediator Clara cell protein (CC16). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Clara cell protein |
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Download Specifications for Anti -CLARA CELL PROTEIN (CC10, CC16, CCPBP, CCSP, Clara cell phospholipid-binding protein, Clara cells 10kD secretory protein, Secretoglobin family 1A member 1, UGB, UP1, Urinary protein 1, Urine Protein 1, Uteroglobin Precursor) |
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