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Clathrin, Light Chain, Isoform a Recombinant, Human
Clathrin, Light Chain, Isoform a Recombinant, Human
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| Clathrin is the main structural component of the lattice covering the cytoplasmic face of the coated pits and coated vesicles in which specific macromolecules are entrapped in the process of receptor-mediated endocytosis. Clathrin is a large, soluble protein composed of heavy chains and light chains. Two genes encode the clathrin light chain proteins. The light chains are believed to be regulatory elements in clathrin function. The brain-specific light chain variant contains an insert encoding 18aa immediately downstream of the region encoding the heavy chain binding domain. | | | Catalog # | C5835-09 | | Source | E. coli | | Applications | Suitable for use as an assay standard in immunological techniques. Other applications not tested. | | Storage and Stability | Aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months. | | Source | E. coli | | Purity | Highly purified | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in Tris, pH 8.0, 0.002% sodium azide, 3mM sodium chloride, 2.5mM imidazole. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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