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Specifications

Clone Host Grade Applications Polyclonal Chicken Affinity Purified E B

Clathrin is the main structural component of the lattice covering the cytoplasmic face of the coated pits and coated vesicles in which specific macromolecules are entrapped in the process of receptor-mediated endocytosis. Clathrin is a large, soluble protein composed of heavy chains and light chains. Two genes encode the clathrin light chain proteins. The light chains are believed to be regulatory elements in clathrin function. The brain-specific light chain variant contains an insert encoding 18aa immediately downstream of the region encoding the heavy chain binding domain. Two transcript variants encoding different isoforms have been found for this gene.
Catalog #	C5835-09A
Applications	Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution	Western Blot: 1:1000-1:2000
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgY
Host	Chicken
Source	Human
Concentration	As reported
Form	Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.
Purity	Purified by immunoaffinity chromatography.
Immunogen	Synthetic peptide corresponding to aa1-211
Specificity	Recognizes human Clathrin, Light Chain, isoform a.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.