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You are here:Home » Antibodies » Abs to Claudin » Anti -Claudin 3 (Claudin-3, CLDN3, C7orf1, Clostridium perfringens Enterotoxin Receptor 2, CPE-receptor 2, CPETR2, CPE-R 2, CPE-R2, CPETR2, Rat Ventral Prostate.1 Protein Homolog, RVP1, hRVP1)

Anti -Claudin 3 (Claudin-3, CLDN3, C7orf1, Clostridium perfringens Enterotoxin Receptor 2,
CPE-receptor 2, CPETR2, CPE-R 2, CPE-R2, CPETR2, Rat Ventral Prostate.1 Protein Homolog,
RVP1, hRVP1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum IH
Claudins are integral membrane proteins involved in the assembly and function of tight junction strands. Claudins have 4 transmembrane domains and 2 extracellular loops and C-terminal tail containing PDZ-binding motifs and YV sequences. Claudin 3, a human homolog of rat RVP1, is a unique member of this family. It is a low-affinity receptor for Clostridium perfringes entertoxin capable of mediating toxin-dependent cytolysis. Claudin-3 has been found to be phosphorylated and up-regulated in various cancer types suggesting a potential role in tumorigenesis.
Catalog #C5838-25C
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 1:50-1:100
Optimal dilutions to be determined by the researcher.
Positive ControlSmall intestine
Cellular Localization
Cytoplasmic and cell membrane
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 0.05% sodium azide.
PuritySerum
ImmunogenSynthetic peptide corresponding to C-terminal of human Claudin 3.
SpecificityRecognizes human Claudin 3. Species Crossreactivity: rat and mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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