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Abs to Claudin
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Anti -Claudin 3 (Claudin-3, CLDN3, C7orf1, Clostridium perfringens Enterotoxin Receptor 2, CPE-receptor 2, CPETR2, CPE-R 2, CPE-R2, CPETR2, Rat Ventral Prostate.1 Protein Homolog, RVP1, hRVP1)
Anti -Claudin 3 (Claudin-3, CLDN3, C7orf1, Clostridium perfringens Enterotoxin Receptor 2, CPE-receptor 2, CPETR2, CPE-R 2, CPE-R2, CPETR2, Rat Ventral Prostate.1 Protein Homolog, RVP1, hRVP1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
IH |
|
| Claudins are integral membrane proteins involved in the assembly and function of tight junction strands. Claudins have 4 transmembrane domains and 2 extracellular loops and C-terminal tail containing PDZ-binding motifs and YV sequences. Claudin 3, a human homolog of rat RVP1, is a unique member of this family. It is a low-affinity receptor for Clostridium perfringes entertoxin capable of mediating toxin-dependent cytolysis. Claudin-3 has been found to be phosphorylated and up-regulated in various cancer types suggesting a potential role in tumorigenesis. | | | Catalog # | C5838-25C | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Small intestine | | Cellular Localization | | | Cytoplasmic and cell membrane | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 0.05% sodium azide. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to C-terminal of human Claudin 3. | | Specificity | Recognizes human Claudin 3. Species Crossreactivity: rat and mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Claudin 3 (Claudin-3, CLDN3, C7orf1, Clostridium perfringens Enterotoxin Receptor 2, CPE-receptor 2, CPETR2, CPE-R 2, CPE-R2, CPETR2, Rat Ventral Prostate.1 Protein Homolog, RVP1, hRVP1) |
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