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You are here:Home » Antibodies » Antibodies-Claudin » Anti -Claudin 3 (CLDN3)

Anti -Claudin 3 (CLDN3)


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Clone Host Grade Applications
Polyclonal Rabbit Purified IH
Tight junctions (TJ) are specialized regions of cell-cell contact that are particularly abundant in luminal epithelial cell sheets. TJ strands on adjacent cells are presumed to interact with each other to form a sort of “molecular gasket” that prevents ions, water and other molecules from leaking between cells. Claudin-3 is expressed in junctions of the duct epithelia and acinar cells as well as uniformly expressed from the periportal to the pericentral hepatocytes in the liver. Also, Claudin-3 was found to be present or secreted by many of the genes up-regulated in ovarian cancer.
Catalog #C5838-26
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: (paraffin-embedded sections). Antigen retrieval by boiling in 10mM sodium citrate (pH 6.0) is needed.
Optimal dilutions to be determined by the researcher.
Posittive ControlColon.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 1% BSA, 0.1% sodium azide.
ImmunogenA synthetic peptide from the C-terminus of mouse Claudin 3.
SpecificityRecognizes mouse Claudin 3. Species Crossreactivity: human and canine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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