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You are here:Home » Antibodies » Abs to Disease Markers » Anti -Claudin 4 (Claudin-4, CLDN4, Clostridium perfringens Enterotoxin Receptor, CPE-receptor, CPER, CPE-R, hCPE-R, CPETR, CPETR1, Williams-Beuren Syndrome Chromosomal Region 8 Protein, WBSCR8)

Anti -Claudin 4 (Claudin-4, CLDN4, Clostridium perfringens Enterotoxin Receptor,
CPE-receptor, CPER, CPE-R, hCPE-R, CPETR, CPETR1, Williams-Beuren Syndrome Chromosomal
Region 8 Protein, WBSCR8)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum IH
Claudin-4 is a member of the claudin family and one of the integral constituents of tight junctions. Tight junctions are the most apical component of intercellular junctional complexes, thereby establishing cell polarity and functioning as major determinants of paracellular permeability. Claudin-4 is overexpressed in the majority of pancreatic carcinomas and functions as a receptor for cytotoxic CPE. It consists of 209 amino acids and contains four putative transmembrane segments. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
Catalog #C5838-37
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 1:100-1:200
Optimal dilutions to be determined by the researcher.
Positive ControlOvarian carcinoma, tonsil
Cellular Localization
Cytoplasmic and cell membrane
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 0.05% sodium azide.
PuritySerum
ImmunogenSynthetic peptide corresponding to C-terminal of human Claudin 4.
SpecificityRecognizes human Claudin 4. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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