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Anti -Claudin 4 (Claudin-4, CLDN4, Clostridium perfringens Enterotoxin Receptor, CPE-receptor, CPER, CPE-R, hCPE-R, CPETR, CPETR1, Williams-Beuren Syndrome Chromosomal Region 8 Protein, WBSCR8)
Anti -Claudin 4 (Claudin-4, CLDN4, Clostridium perfringens Enterotoxin Receptor,
CPE-receptor, CPER, CPE-R, hCPE-R, CPETR, CPETR1, Williams-Beuren Syndrome Chromosomal
Region 8 Protein, WBSCR8)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
IH |
|
| Claudin-4 is a member of the claudin family and one of the integral constituents of tight junctions. Tight junctions are the most apical component of intercellular junctional complexes, thereby establishing cell polarity and functioning as major determinants of paracellular permeability. Claudin-4 is overexpressed in the majority of pancreatic carcinomas and functions as a receptor for cytotoxic CPE. It consists of 209 amino acids and contains four putative transmembrane segments. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. | | | Catalog # | C5838-37 | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 1:100-1:200 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Ovarian carcinoma, tonsil | | Cellular Localization | | | Cytoplasmic and cell membrane | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 0.05% sodium azide. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to C-terminal of human Claudin 4. | | Specificity | Recognizes human Claudin 4. Species Crossreactivity: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Claudin 4 (Claudin-4, CLDN4, Clostridium perfringens Enterotoxin Receptor, CPE-receptor, CPER, CPE-R, hCPE-R, CPETR, CPETR1, Williams-Beuren Syndrome Chromosomal Region 8 Protein, WBSCR8) |
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