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Anti -Claudin 11 (OSP, Oligodendrocyte Specific Protein, CLDN11)
Anti -Claudin 11 (OSP, Oligodendrocyte Specific Protein, CLDN11)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
FC |
|
| Claudin-11 is a 207aa multipass membrane protein in the claudin family of epithelial tight junction proteins. Claudin-11 is widely expressed and is involved in epithelial remodeling during spermatogenesis and inner ear mechanotransduction. Claudin-11 is upregulated in some cancers. Human Claudin-11 shares 94% aa sequence identity with mouse and rat Claudin-11. | | | Catalog # | C5838-62A | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 25ug/ml; 10ul labels 1-2.5x10e5 cells in a total reaction volume not exceeding 200ul. Validated using OVCAR-3 cells. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b | | Clone No | 7H208 | | Host | Mouse | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Recombinant corresponding to human Claudin-11 expressed in NSO cell (Accession # NP_005593). | | Specificity | Recognizes human Claudin-11. Stains human Claudin-11 transfectants but not irrelevant transfectants. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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