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You are here:Home » Antibodies » Abs to Claudin » Anti -Claudin 11 (OSP, Oligodendrocyte Specific Protein, CLDN11)

Anti -Claudin 11 (OSP, Oligodendrocyte Specific Protein, CLDN11)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Claudin-11 is a 207aa multipass membrane protein in the claudin family of epithelial tight junction proteins. Claudin-11 is widely expressed and is involved in epithelial remodeling during spermatogenesis and inner ear mechanotransduction. Claudin-11 is upregulated in some cancers. Human Claudin-11 shares 94% aa sequence identity with mouse and rat Claudin-11.
Catalog #C5838-62A
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 25ug/ml; 10ul labels 1-2.5x10e5 cells in a total reaction volume not exceeding 200ul. Validated using OVCAR-3 cells.
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Clone TypeMonoclonal
IsotypeIgG2b
Clone No7H208
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant corresponding to human Claudin-11 expressed in NSO cell (Accession # NP_005593).
SpecificityRecognizes human Claudin-11. Stains human Claudin-11 transfectants but not irrelevant transfectants.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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