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You are here:Home » Antibodies » Abs to Claudin » Anti -CLDN14 (Claudin-14, UNQ777/PRO1571)

Anti -CLDN14 (Claudin-14, UNQ777/PRO1571)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
These proteins consist of 4 hydrophobic transmembrane domains, 2 extracellular loops and short cytoplasmic tails at N and C-termini containing YV and PDZ-domain binding motifs. Claudin 14, a 25kD glycoprotein, is a novel member of this family. It is a vital component of inner ear tight junction strands. Its expression has been observed in sensory epithelium of inner organ of Corti, vestibular system, kidney and Liver. Mutations in Claudin 14 cause a congenital autosomal recessive form of nonsyndromic sensorineural deafness in humans.
Catalog #C5838-75C
ApplicationsSuitable for use in Western Blot and ELISA. Other applications not tested.
Recommended DilutionWestern Blot: 1-3ug/ml
ELISA: >1:128,000
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Duodenal lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to SATHSGYRLNDYV, from the C-terminus of the protein sequence according to NP_036262; NP_652763.
SpecificityRecognizes human Claudin 14. Species sequence homology: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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