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You are here:Home » Antibodies » Abs to Lectins » Anti -CLEC4D (C-type Lectin Domain Family 4 Member D, CLCSF8, CLEC6, MCL)

Anti -CLEC4D (C-type Lectin Domain Family 4 Member D, CLCSF8, CLEC6, MCL)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B FC
CLEC4D (C-type lectin domain family 4 member D), also known as CLCSF8, CLEC-6, and MCL, is a 30kD type II transmembrane (TM) glycoprotein that belongs to the CLR (C-type Lectin Receptor) family of molecules. It is synthesized as a 215 amino acid (aa) protein that contains a 17 aa N-terminal cytoplasmic domain, a 21 aa TM segment, and a 177 aa C-terminal extracellular region. The extracellular region shows a short stalk and a 118 aa CRD (carbohydrate recognition domain). The nature of its carbohydrate ligand is unknown. CLEC4D is restricted to monocytes/macrophages and serves as an endocytic receptor. Homodimers and homotrimers form on the cell surface. The human CLEC4D extracellular region shares 63% aa sequence identity with the mouse extracellular region.
Catalog #C5839-65
ApplicationsSuitable for use in Western Blot, Flow Cytometry and ELISA. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Flow Cytometry: 25ug/ml
ELISA: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No7H219
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile, ddH2O or sterile 40-50% glycerol.
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0-derived recombinant human CLEC4D (aa52-215) Accession # Q8WXI8
SpecificityRecognizes human CLEC4D.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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