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Anti -CLEC4D (C-type Lectin Domain Family 4, Member D, C-type Lectin Superfamily Member 8, C-type Lectin-like Receptor 6, CLEC-6, CLECSF8, MCL) (PE)
Anti -CLEC4D (C-type Lectin Domain Family 4, Member D, C-type Lectin Superfamily Member 8,
C-type Lectin-like Receptor 6, CLEC-6, CLECSF8, MCL) (PE)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
FC |
|
| CLEC4D (C-type lectin domain family 4 member D), also known as CLCSF8, CLEC-6, and MCL, is a 30kD type II transmembrane (TM) glycoprotein that belongs to the CLR (C-type Lectin Receptor) family of molecules. It is synthesized as a 215aa protein that contains a 17aa N-terminal cytoplasmic domain, a 21aa TM segment, and a 177aa C-terminal extracellular region. The extracellular region shows a short stalk and a 118aa CRD (carbohydrate recognition domain). The nature of its carbohydrate ligand is unknown. CLEC4D is restricted to monocytes/macrophages and serves as an endocytic receptor. Homodimers and homotrimers form on the cell surface. | | | Catalog # | C5839-65B | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilutions | Optimal dilutions to be determined by the researcher. | | Hybridoma | Myeloma with B cells from Balb/c mice. | | Storage and Stability | May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b | | Clone No | 11C7 | | Host | Mouse | | Source | Human | | Concentration | ~0.02mg/ml | | Form | Supplied as a liquid in sodium chloride, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE). | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Purified, NS0-derived, recombinant human CLEC4D (aa52-215; Accession # Q8WXI8). | | Specificity | Recognizes human CLEC4D. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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