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You are here:Home » Antibodies » Antibodies-Lectins » Anti -CLEC4D (C-type Lectin Domain Family 4, Member D, C-type Lectin Superfamily Member 8, C-type Lectin-like Receptor 6, CLEC-6, CLECSF8, MCL) (PE)

Anti -CLEC4D (C-type Lectin Domain Family 4, Member D, C-type Lectin Superfamily Member 8,
C-type Lectin-like Receptor 6, CLEC-6, CLECSF8, MCL) (PE)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
CLEC4D (C-type lectin domain family 4 member D), also known as CLCSF8, CLEC-6, and MCL, is a 30kD type II transmembrane (TM) glycoprotein that belongs to the CLR (C-type Lectin Receptor) family of molecules. It is synthesized as a 215aa protein that contains a 17aa N-terminal cytoplasmic domain, a 21aa TM segment, and a 177aa C-terminal extracellular region. The extracellular region shows a short stalk and a 118aa CRD (carbohydrate recognition domain). The nature of its carbohydrate ligand is unknown. CLEC4D is restricted to monocytes/macrophages and serves as an endocytic receptor. Homodimers and homotrimers form on the cell surface.
Catalog #C5839-65B
ApplicationsSuitable for use in Flow Cytometry, ELISA and Western Blot. Other applications not tested.
Recommended DilutionsFlow Cytometry: 10ul/10e6 cells, human periferal blood monocytes
Optimal dilutions to be determined by the researcher.
HybridomaMyeloma with B cells from Balb/c mice.
Storage and StabilityStore product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No11C7
HostMouse
SourceHuman
Concentration~0.02mg/ml
FormSupplied as a liquid in sodium chloride, 0.5% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
PurityPurified by Protein A/G affinity chromatography.
ImmunogenPurified, NS0-derived, recombinant human CLEC4D (aa52-215; Accession # Q8WXI8).
SpecificityRecognizes human CLEC4D. Does not cross react with rhCLECSF9, rhCLECSF13, rhOCIL or rhOCILrp2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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