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Anti -CLEC4E (C-type lectin domain family 4, member E)
Anti -CLEC4E (C-type lectin domain family 4, member E)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IH IF |
|
| CLEC4E is a diverse family of protein which was originally defined by their ability to recognize a wide range of ligand of carbohydrate structure. CLEC4E expressed in macrophages subjected to several types of stress. It plays an essential role in response to trehalose-6,6'-dimycolate (TDM) and activated by a synthetic analogue, trehalose dibehenate (TDB). Recently it was reported that CLEC4E is associated with an immunoreceptor tyrosine-based activation motif-containing Fc receptor gamma-chain (FcR-gamma) and functions as an activating receptor for damaged self- and non-self-pathogenic fungi. | | | Catalog # | C5839-66 | | Applications | Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence. Other applications not tested. | | Recommended Dilutions | Western Blot: 1:1000 | | Immunohistochemistry (Paraffin): 1:50. Incubated for 2 hours at RT. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB). | | Immunofluorescence (IF-IC): 1:500 | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Mouse F0 myeloma cells with spleen cells from BALB/c mice. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b,k | | Clone No | 10K398 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide. | | Purity | Purified by Protein G affinity chromatography. ( 95% SDS-PAGE) | | Immunogen | Recombinant corresponding to aa41-219 from human CLEC4E expressed in E. coli (NP_055173). | | Specificity | Recognizes human CLEC4E. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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