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Specifications

Clone Host Grade Applications Polyclonal Rabbit Serum B IP

CLOCK, a basic helix-loop-helix (bHLH)/PAS protein, is an important factor in the molecular clock mechanism. Mutations in this protein lead to abnormal circadian behavior and defective transcriptional activity. CLOCK has been shown to interact strongly with other bHLH-PAS proteins such as MOP3, a BMAL1 isoform.
Catalog #	C5843-01A
Applications	Suitable for use in Western Blot and Chromatin Immunoprecipitation. Other applications not tested.
Recommended Dilutions	Western Blot: 1:1000
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Rabbit
Source	Mouse
Concentration	Not Determined
Form	Supplied as a liquid, 0.05% sodium azide.
Purity	Serum
Immunogen	Two peptides derived from mouse CLOCK, conjugated to albumin.
Cellular Localization	Cytoplasmic and nuclear. Shuffling between the cytoplasm and the nucleus is under circadian regulation and is BMAL1-dependent. Phosphorylated form located in the nucleus
Specificity	Recognizes mouse CLOCK. Species Crossreactivity: human
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	5330400M04Rik, Circadian locomoter output cycles protein kaput, mCLOCK, mKIAA0334