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You are here:Home » Antibodies » Abs to Circadian Proteins » Anti -Clock

Anti -Clock

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Clock is a basic helix-loop helix (bHLH) transcription factor that regulates circadian rhythms and sleep cycles. Clock contain a DNA-binding domain, a protein dimerization domain that heterodimerizes with BMAL1 and a glutamine-rich C terminus region. Clock dimerization with BMAL helps regulate nuclear translocation and binding of Clock to the E box elements stimulates circadian genes transcription.
Catalog #C5843-02A
ApplicationsSuitable for use in Western Blot. Other applications have not been tested.
Recommended DilutionsWestern Blot: 0.5-4 ug/ml
Optimal dilutions to be determined by the researcher.
Control Peptide C5843-02A1
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
PurityPurified by immunoaffinitiy chromatography.
ImmunogenSynthetic peptide surrrounding aa842 of mouse Clock.
SpecificityRecognizes the 100kD and the ~62kD isoforms of mouse CLOCK. Species Crossreactivity: human, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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