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You are here:Home » Antibodies » Antibodies-Proteins » Anti -Clock

Anti -Clock


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Clone Host Grade Applications
Polyclonal Sheep Affinity Purified E B
Clock is an essential regulator of circadian rhythms. Clock is a basic helix-loop-helix-PAS transcription factor that heterodimerizes with BMAL1. Together these transcription factors bind to E box elements (CACGTG) within the promoter of circadian genes (period1 and 2) stimulating their transcription. BMAL dimerization is necessary for Clock’s nuclear translocation, E box dependent transcription, phosphorylation, and degradation.
Catalog #C5843-16
ApplicationsSuitable for use in ELISA, Western Blotting. Other applications not tested.
Recommended DilutionWestern Blotting: 0.5ug/mL
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
FormSupplied as a lyophilized powder in PBS, 0.02% trehalose. Reconstitute with 1ml sterile 40-50% glycerol, PBS.
PurityPurified by immunoaffinity chromatography.
ImmunogenE. coli-derived recombinant human Clock.
SpecificityRecognizes human Clock.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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