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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CMKLR1 (Chemokine-Like Receptor 1, CHEMERINR, ChemR23, DEZ, G-Protein Coupled Receptor ChemR23, G-Protein Coupled Receptor DEZ, MGC126105, MGC126106)

Anti -CMKLR1 (Chemokine-Like Receptor 1, CHEMERINR, ChemR23, DEZ, G-Protein Coupled
Receptor ChemR23, G-Protein Coupled Receptor DEZ, MGC126105, MGC126106)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified FC
Serpentine chemokine-like receptor 1 (CMKLR1) is a novel chemoattractant receptor, which is also referred to Chem23 or DEZ. CMKLR1 is expressed on plasmacytoid dendritic cells (pDC) in blood but is not expressed on myeloid dendritic cells, lymphocytes, monocytes or granulocytes. Studies show that CMKLR1 is also expressed on dendritic cells, which have been generated in vitro from monocytes. The sole ligand for CMKLR1 is chemerin, a chemoattractant that exists at the mRNA level in a wide range of tissues, and as an inactive proform in serum and plasma. Studies suggest that chemerin, in plasma, is converted into a potent pDC attractant following blood coagulation and may be a process by which pDCís are recruited to sites of bleeding and tissue damage.
Catalog #C5895-01H
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:25-1:100; 10ul labels 10e6 cells in 100ul
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10B2266
HostRat
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenPeptide corresponding to an epitope within the N-terminal region of human CMKLR1.
SpecificityRecognizes human CMKLR1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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