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You are here:Home » Antibodies » Abs to Enzymes, Polymerase » Anti -Cofactor Required for Sp1 Transcriptional Activation Subunit 8, 34kDa (CRSP Complex Subunit 8, CRSP8, CRAP34, CRSP34, Mediator Complex Subunit 27, MED27, Mediator of RNA Polymerase II Transcription Subunit 27, MGC11274, p37 TRAP/SMCC/PC2 Subunit, Transcri

Anti -Cofactor Required for Sp1 Transcriptional Activation Subunit 8, 34kDa (CRSP Complex
Subunit 8, CRSP8, CRAP34, CRSP34, Mediator Complex Subunit 27, MED27, Mediator of RNA
Polymerase II Transcription Subunit 27, MGC11274, p37 TRAP/SMCC/PC2 Subunit, Transcri

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Catalog #C7506-01V-HRP
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1000
ELISA: 1ug/ml-3ng/ml
Optimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Labeled with horseradish peroxidase (HRP). Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10B2605
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free). Conjugated to HRP.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant protein corresponding to a portion of amino acids within aa1-71 of human CRSP8.
SpecificityRecognizes human CRSP8.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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