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Anti -COL1A1 (Collagen alpha-1(I) Chain, Alpha-1 Type I Collagen)
Anti -COL1A1 (Collagen alpha-1(I) Chain, Alpha-1 Type I Collagen)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IH |
|
| COL1A1 is the major component of type I collagen, and the sole component of the collagen located in cartilage. COL1A1 mutations are associated with osteogenesis imperfecta type I, II, III, and IV, Ehlers-Danlos syndrome type I and II, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a skin tumor called dermatofibrosarcoma protuberans. Two COL1A1 transcripts arise from variant polyadenylation signals for this gene. | | | Catalog # | C7510-11Q1 | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG3,k | | Clone No | 3G3 | | Host | Mouse | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Recombinant corresponding to human COL1A1. | | Specificity | Recognizes human COL1A1. Species sequence homology: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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