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You are here:Home » Antibodies » Abs to Collagen » Anti -Collagen Type I

Anti -Collagen Type I

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Highly Purified E IH IF RIA
Type I collagen is the most common of the collagens in vertebrates. It comprises up to 90% of the skeletons of the mammals and is also widespread all over the body. Such as: skin, tendons, ligaments, cornea, intervertebral disks, dentine, arteries and granulation tissues as the main locations. The importance of type I collagen for medical research is that it is involved in many human and animal diseases, including fibrosis, osteoporosis, cancer, atherosclerosis etc. Type I
collagen is frequently utilized to monitor physiological changes in tissues as well as being used as diagnostic tools in various pathological conditions.
Catalog #C7510-14C
ApplicationsSuitable for use in RIA, Immunofluorescence, Immunohistochemistry and ELISA. Other applications not tested.
Recommended DilutionRIA Titer: 1:500
Indirect Immunofluorescence (frozen human liver, skin, placenta): 1:80
Immunohistochemistry: 1:500 Fixed, paraffin-embedded human tissues (skin, liver, placenta).
ELISA: 1:200
Optimal dilutions to be determined by the researcher.
Recommended Secondary Antibodies (IF)I1904-40D: IgG, H&L (FITC) Pab Gt x Rb
I1904-40M: IgG, Fc, X-Adsorbed (FITC) Pab Gt x Rb
I1904-41: IgG, X-Adsorbed (FITC) Pab Gt x Rb
I1904-41B: IgG, F(ab')2 (FITC) Pab Gt x Rb
I1904-41G: IgG, F(ab')2, X-Adsorbed (FITC) Pab Gt x Rb
I1904-46N: IgG, H&L (FITC) Pab Gt x Rb
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid. No preservative added.
PurityPuri ed by ion exchange chromatography (DEAE-Trisacryl).
ImmunogenCollagen type I extracted and puri ed from human skin.
SpecificityRecognizes human Collagen Type I. Crossreactivity (RIA%)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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