Anti -Collagen Type IV (Arresten, ASLN, ATS, CA54, Canstatin, COL4A1, COL4A2, Collagen
Alpha 1(IV) Chain, Collagen Alpha 2(IV) Chain, Collagen IV Alpha 1 Polypeptide, Collagen
IV Alpha 2 Polypeptide, Collagen of Basement Membrane Alpha 1 Chain, Collagen of Base
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
E IH |
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| Catalog # | C7510-50D | | Collagen IV is a major constituent of the basement membranes along with laminins and enactins. It is composed of a1(IV) chain and a2(IV) chain in 2 | 1 ratio . It can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas. | | Excellent for the staining of routine formalin-fixed, paraffinembedded tissues. | | Applications | Immunohistology (Formalin/paraffin): (Use Ab at 1:50-1:100 for 30 min at RT) (Staining of formalin/paraffin tissues is enhanced by digestion of tissue sections with Protease XXV at 1mg/ml PBS for 5 minutes at 37°C. | | Positive Control | Skin | | Cellular Localization | Basement membrane | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1+IgG1 | | Clone No | 5G84 | | Host | Mouse | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid with 0.09% sodium azide. | | Purity | Culture supernatant | | Immunogen | Human glomeruli | | Specificity | Highly specific to type IV collagen. In kidney, Ab reacts with glomerular and tubular basement membranes, parts of mesangial matrix and the Bowman’s capsule. It also reacts with basal lamina of capillaries as well as basement membranes in a variety of tissues. Species Crossreactivity: Human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Collagen Type IV (Arresten, ASLN, ATS, CA54, Canstatin, COL4A1, COL4A2, Collagen Alpha 1(IV) Chain, Collagen Alpha 2(IV) Chain, Collagen IV Alpha 1 Polypeptide, Collagen IV Alpha 2 Polypeptide, Collagen of Basement Membrane Alpha 1 Chain, Collagen of Base |
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