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You are here:Home » Antibodies » Abs to Collagen » Anti -Collagen IV

Anti -Collagen IV

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E B IH
The collagen family is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral selfassociation in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function, such as bone strength and platelet activation.
Catalog #C7510-50V
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry (Frozen, paraffin): 1:1000 on formalin fixed, paraffin embedded and enzyme treated human tongue sections.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8J1049
HostMouse
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid, 15mM sodium azide.
PurityAscites
ImmunogenHuman collagen type IV
SpecificityRecognizes native, undenatured human Collagen IV . Using immunohistochemical staining of basal laminae, recognizes an epitope located on the alpha1 and/or alpha2 chains of human Collagen IV. Does not crossreact with human collagen types I, II, III, V, VI, or VII. Does not react with human vitronectin, fibronectin or chondroitin sulfate types A, B and C.
Species CrossreactivityPrimate
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesArresten, ASLN, ATS, CA54, Canstatin, COL4A1, COL4A2, Collagen Alpha 1(IV) Chain, Collagen Alpha 2(IV) Chain, Collagen IV Alpha 1 Polypeptide, Collagen IV Alpha 2 Polypeptide, Collagen Of Basement Membrane Alpha 1 Chain, Collagen Of Basement Membrane Alph


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