Anti -Collagen Type V (Collagen-V, Alpha 1 Type V Collagen, Collagen alpha-1(V) Chain,
Collagen Type V alpha 1, Col5A1, Alpha 2 Type V Collagen, Collagen alpha-2(V) Chain,
Collagen Type V alpha 2, Collagen V alpha 2 Polypeptide, Col5A2, Collagen alpha-3(V) Chai
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E IH |
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| Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. | | | Catalog # | C7510-56M | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 1:20. Requires pre-treatment with 1mg/ml pepsin in 0.5M acetic acid for 2 hours at 37ºC and multiple buffer washes is recommended. | | Immunohistochemistry (Frozen):1:20 | | ELISA: 1:1500 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O, 1% BSA, 0.09% sodium azide. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.1mg/ml (after reconstitution) | | Form | Supplied as a lyophilized powder from PBS/BBS, 1% dextran, 1% mannitol. Reconstitute with 500ul ddH2O, 1% BSA, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Collagen V from human placenta. | | Specificity | Recognizes human collagen type V 100%. Crossreactivity: human collagen type IV <5%, human collagen type I and III collagen <3%, human plasma proteins <0.5%. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | COL5A2 Protein, Collagen alpha-2(V) Chain Precursor, OTTHUMP00000064637 |
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Download Specifications for Anti -Collagen Type V (Collagen-V, Alpha 1 Type V Collagen, Collagen alpha-1(V) Chain, Collagen Type V alpha 1, Col5A1, Alpha 2 Type V Collagen, Collagen alpha-2(V) Chain, Collagen Type V alpha 2, Collagen V alpha 2 Polypeptide, Col5A2, Collagen alpha-3(V) Chai |
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