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You are here:Home » Antibodies » Abs to Collagen » Anti -Collagen Type V (Collagen-V, Alpha 1 Type V Collagen, Collagen alpha-1(V) Chain, Collagen Type V alpha 1, Col5A1, Alpha 2 Type V Collagen, Collagen alpha-2(V) Chain, Collagen Type V alpha 2, Collagen V alpha 2 Polypeptide, Col5A2, Collagen alpha-3(V) Chai

Anti -Collagen Type V (Collagen-V, Alpha 1 Type V Collagen, Collagen alpha-1(V) Chain,
Collagen Type V alpha 1, Col5A1, Alpha 2 Type V Collagen, Collagen alpha-2(V) Chain,
Collagen Type V alpha 2, Collagen V alpha 2 Polypeptide, Col5A2, Collagen alpha-3(V) Chai

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E IH
Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II.
Catalog #C7510-56M
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 1:20. Requires pre-treatment with 1mg/ml pepsin in 0.5M acetic acid for 2 hours at 37ºC and multiple buffer washes is recommended.
Immunohistochemistry (Frozen):1:20
ELISA: 1:1500
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O, 1% BSA, 0.09% sodium azide. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.1mg/ml (after reconstitution)
FormSupplied as a lyophilized powder from PBS/BBS, 1% dextran, 1% mannitol. Reconstitute with 500ul ddH2O, 1% BSA, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenCollagen V from human placenta.
SpecificityRecognizes human collagen type V 100%. Crossreactivity: human collagen type IV <5%, human collagen type I and III collagen <3%, human plasma proteins <0.5%.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCOL5A2 Protein, Collagen alpha-2(V) Chain Precursor, OTTHUMP00000064637


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