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You are here:Home » Antibodies » Abs to Collagen » Anti -Collagen Type VII

Anti -Collagen Type VII

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant E IH
Type VII collagen is a newly characterized collagen which appears to be the major component of the anchoring fibril.
Type VII collagen fibrils are composed of three identical alpha collagen chains. It's location is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in the collagen V11 gene are associated with all forms of dystrophic epidermolysis bullosa.
Catalog #C7510-64B
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Frozen): 1:5-1:10
Optimal dilutions to be determined by the researcher.
Recommended Secondary AntibodiesI1904-65V: IgG (FITC) Pab RbxMo
I1904-66A IgG X-Adsorbed (FITC) Pab RbxMo
I1904-65W: IgG (HRP) Pab RbxMo
I1904-66C: IgG X-Adsorbed (HRP) Pab RbxMo
HybridomaSp2 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG1
Clone No3H2036
HostMouse
ConcentrationNot determined
FormSupplied as a liquid in 0.2M Tris/HCl pH 7.4, 5-10% fetal calf serum, 0.09% sodium azide.
PuritySupernatant
ImmunogenCrude extract of skin.
SpecificityRecognizes the carboxyterminus of type VII collagen. Species Crossreactivity: human. Does not react with rat, mouse or porcine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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