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You are here:Home » Antibodies » Abs to Neuroscience » Anti -Collapsin Response Mediator Protein 4 (CRMP4, DPYSL3, DRP-3, DRP3, ULIP, Dihydropyrimidinase-like 3)

Anti -Collapsin Response Mediator Protein 4 (CRMP4, DPYSL3, DRP-3, DRP3, ULIP,
Dihydropyrimidinase-like 3)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
DRP-3 belongs to the hydantoinase/dihydropyrimidase subfamily. It is required for signalling by class 3 semaphorins and remodelling of the cytoskeleton. It also plays a role in axon guidance, neuronal growth cone collapse and cell migration. It exists as a homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL4 or DPYSL5. The unprocessed precursor is 570 amino acids long and has an estimated molecular weight of 61.9kD. It is mainly expressed in heart and skeletal muscle, but is also strongly expressed in fetal brain and spinal cord. It localizes to the cytoplasm and growth cone. This protein interacts with synaptic vesicle protein 2 and SH3A domain of intersectin.
Catalog #C7517-08H
ApplicationsSuitable for use in Direct ELISA and Western Blot. Other applications have not been tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No9G340
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
PurityPurified by affinity chromatography.
ImmunogenPartial recombinant protein of human DRP-3 (aa457 to 556) with a GST tag.
SpecificityRecognizes human DRP-3. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDihydropyrimidinase-related protein 3, unc-33-like phoshoprotein, ULIP protein, collapsin response mediator protein 4, CRMP-4, GENE NAME: DPSYL3, CRMP4, DRP3, ULIP


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