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You are here:Home » Antibodies » Abs to Extracellular Matrix Proteins » Anti -COMP (Cartilage Oligomeric Matrix Protein Precursor, EDM1, EPD1, Epiphyseal Dysplasia 1, Epiphyseal Dysplasia 1 Multiple, MED, MGC13181, MGC149768, PSACH, Pseudoachondroplasia, THBS5, Thrombospondin 5)

Anti -COMP (Cartilage Oligomeric Matrix Protein Precursor, EDM1, EPD1, Epiphyseal
Dysplasia 1, Epiphyseal Dysplasia 1 Multiple, MED, MGC13181, MGC149768, PSACH,
Pseudoachondroplasia, THBS5, Thrombospondin 5)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IH
COMP is a non-collagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
Catalog #C7849-09A
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 1:200-1:1000
Western Blot: 1:200-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
ConcentrationNot Determined
FormLyophilized Whole Rabbit antisera. Reconstitute with 200ul distilled H20. No preservative added.
PuritySerum
ImmunogenA 16 residue synthetic peptide to Complex Oligomatrix Protein.
SpecificityReacts specifically with COMP from cartilage matrix. Species Crossreactivity: Human, mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCartilage oligomeric matrix protein precursor, EDM1, EPD1, Epiphyseal dysplasia 1, Epiphyseal dysplasia 1 multiple, MED, MGC13181, MGC149768, PSACH, Pseudoachondroplasia, THBS5, Thrombospondin 5, Thrombospondin5


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