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Compound 401 (2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one)
Compound 401 (2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one)
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| Cell-permeable. A reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) (IC = 0.28uM) that also targets mTOR (IC50 = 5. 3uM), but not PI 3-K in vitro. Induces apoptosis in vitro. | | | Catalog # | C7849-74 | | Solubility | DMSO (10mM), EtOH (5mM) | | Molecular Weight | ~281.31 | | CAS Number | 168425-64-7 | | Molecular Formula | C H N O | | Molecular Weight | ~281.31 | | Purity | ~97% (HPLC) | | Concentration | Not determined | | Form | Supplied as a white to off-white solid. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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