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You are here:Home » Biochemicals » Biochem-Inhibitors » Compound 401 (2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one)

Compound 401 (2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one)


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Cell-permeable. A reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) (IC = 0.28uM) that also targets mTOR (IC50 = 5. 3uM), but not PI 3-K in vitro. Induces apoptosis in vitro.
Catalog #C7849-74
SolubilityDMSO (10mM), EtOH (5mM)
Molecular Weight~281.31
CAS Number168425-64-7
Molecular FormulaC H N O
Molecular Weight~281.31
Purity~97% (HPLC)
ConcentrationNot determined
FormSupplied as a white to off-white solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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