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You are here:Home » Antibodies » Abs to Complement » Anti -Complement 1s (Complement Component 1 s Subcomponent, Basic Proline-rich Peptide IB-1, C1 Esterase, Complement C1s Subcomponent Precursor)

Anti -Complement 1s (Complement Component 1 s Subcomponent, Basic Proline-rich Peptide
IB-1, C1 Esterase, Complement C1s Subcomponent Precursor)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Serum E
Catalog #C7850-08J
C1 component of human complement is a complex of three glycoproteins C1q, C1r and C1s. C1s has a molecular weight of 83000 and is present in plasma in an average concentration of 50mg/ml, either as a complex with C1q and C1s or in the absence of C1q as a tetramer with C1s. The subcomponents of the C1 complex are responsible for the initiation of the classical pathway of complement activation.
ApplicationsSuitable for use in use ELISA, Immunoelectrophoresis and Radial Immunodiffusion. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder. Preservative free. Reconstitute with 1ml sterile ddH2O. Dilute further in PBS, pH 7.2.
PuritySerum
ImmunogenHuman C1s isolated as a homogenous protein
SpecificityRecognizes human C1s. In immunoelectrophoresis and radial immunodiffusion (Ouchterlony) against fresh normal human plasma a single precipitin line is obtained which shows a reaction of identity with the precipitin line obtained with purified C1s protein. May also react with complexes containing C1q. No reaction is obtained with C1q, C1r or any other plasma protein component or serum. Does not crossreact with any other component of human plasma.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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