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Specifications

Clone Host Grade Applications Monoclonal Mouse Affinity Purified B IP

The complement system is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead to the cleavage of the third complement component C3. C3 is cleaved into C3a and C3b, where C3b becomes attached to immune complexes. Futhermore C3b plays a critical role in the amplification loop of the alternative pathway.
Catalog #	C7850-10N
Applications	Suitable for use in IA, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended Dilution	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG2b
Clone No	8J442
Host	Mouse
Concentration	~0.1mg/ml
Form	0.02% Sodium Azide; 0.1% BSA, PBS
Purity	Purified by Protein G affinity chromatography.
Specificity	This antibody reacts with an epitope on C3b and recognizes cleaved C3b and full C3 which plays a central role in the complement system. Species Crossreactivity: Crossreacts with Human.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	Complement component 3, ASP, Complement C3 precursor, CPAMD1, Acylation Stimulating Protein Cleavage Product