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You are here:Home » Antibodies » Abs to Complement » Anti -Complement C3 (C3, C3b, Complement C3 beta Chain)

Anti -Complement C3 (C3, C3b, Complement C3 beta Chain)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant E B IP
The complement factor C3 consists of an alpha- and a beta-chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical and mannose binding lectin activation pathways lead to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to formation of the alpha- chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues including renal epithelial cells and hepatocytes.
Catalog #C7850-13F
ApplicationsSuitable for use in Western Blot, ELISA and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgM
Clone No13A32
HostMouse
SourceRat
ConcentrationNot determined
FormSupplied as a liquid, 0.02% sodium azide.
PuritySupernatant
SpecificityRecognizes an epitope on rat C3b. The antibody reacts both with intact C3 and C3b.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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