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You are here:Home » Antibodies » Abs to Peptides » Anti -Complement C3a (C3 and PZP-like alpha-2-macroglobulin Domain-containing Protein 1, C3, Complement C3 alpha Chain, CPAMD1) (APC)

Anti -Complement C3a (C3 and PZP-like alpha-2-macroglobulin Domain-containing Protein 1,
C3, Complement C3 alpha Chain, CPAMD1) (APC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Complement Component 3a receptor (C3a R) is an ~90kD G protein-coupled 7 transmembrane sulfated glycoprotein expressed on myeloid peripheral blood leukocytes, and on activated lymphocytes, endothelial and internal organ epithelial cells. Engagement of C3a R by C3a activates mast cells and neutrophils, triggering degranulation in airways during asthmatic allergen challenges. It assists in Th2-type inflammatory reactions and stimulates leukocyte chemotaxis.
Catalog #C7850-13L
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
HybridomaMyeloma with B cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing Allophycocyanin conjugates will result in a substantial loss of enzymatic activity.
Clone TypeMonoclonal
IsotypeIgG2A
Clone No11C9
HostMouse
SourceHuman
Concentration~0.01mg/ml
FormSupplied as a liquid in sodium chloride, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
PurityPurified by Protein G affinity chromatography.
ImmunogenHuman Complement C3a R transfected NS0 cells (rhC3a R; Accession # NP_000055).
SpecificityRecognizes human Complement C3a R.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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