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You are here:Home » Molecular Biology » MB-Complement » Complement C3, C3b, Human (Complement C3 beta Chain, Complement Component C3b, Complement C3b alpha Chain, C3/C3b, Acylation Stimulating Protein Cleavage Product, ASP, Complement Component 3, Complement Factor 3, CPAMD1)

Complement C3, C3b, Human (Complement C3 beta Chain, Complement Component C3b, Complement
C3b alpha Chain, C3/C3b, Acylation Stimulating Protein Cleavage Product, ASP, Complement
Component 3, Complement Factor 3, CPAMD1)

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Specifications

Cleavage of the C3-alpha chain at peptide bond 77 results in production of C3a and C3b fragments. The C3b fragment is a glycoprotein composed of the modified C3-alpha chain and the intact C3-beta chain. Nascent C3b has the transient ability to form a covalent ester bond with a variety of target surfaces. Once bound to target surfaces C3b becomes an essential subunit of both the classical and alternative pathway C5 cleaving enzymes.
Catalog #C7850-13Z
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight180kD
SourceHuman serum
Purity~90% by SDS-PAGE
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2. Preservative free
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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