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You are here:Home » Molecular Biology » MB-Complement » Complement C3c, Human

Complement C3c, Human


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Human C3c produced in Human Plasma having a molecular mass of 180kD. The C3c component is central in both complement activation pathways, with different specific proteolytic systems cleaving it to form C3 convertase. Cleavage of C3 releases C3a and the C3b fragment which is part of the alternative C3 convertase. C3 levels can be low because of decreased synthesis or due to consumption. High C3 levels are seen in highly acute or chronic inflammation, hepatic cholestasis and during the third trimester of pregnancy.
Catalog #C7850-14A1
SolubilityIt is recommended to reconstitute the lyophilized hC3c in de-ionized water.
StabilityHuman C3c although stable at room temperature for 3 weeks, should be stored between 2-80C.
Molecular Weight180kD
SourceHuman Plasma
FormSupplied as a lyophilized powder in sodium phosphate buffer, pH 7.2, containing 0.15M sodium chloride. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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