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You are here:Home » Antibodies » Abs to Complement » Anti -Complement C3, C3c

Anti -Complement C3, C3c

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Serum E
C3c is the major fragment resulting from the C3 cleavage by C3 convertase and factor i. It is
composed of an intact beta chain bound to two fragments of the alpha chain.
Catalog #C7850-14S
ApplicationsSuitable for use in Immunoelectrophoresis and ELISA. Other applications not tested.
Recommended DilutionImmunoelectrophoresis: 120ul against 2ul canine plasma or equivalent
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceCanine
ConcentrationNot determined
FormSupplied as a lyophilized powder. Preservative free. Reconstitute with 1ml sterile ddH2O. Dilute further in PBS, pH 7.2.
PuritySerum
ImmunogenC3c isolated and purified from pooled normal canine serum.
SpecificityRecognizes canine C3, C3c. In IEP against fresh canine serum, a single precipitin line is obtained in the beta-1 region representing native C3. Against serum containing partly activated C3, a precipitin line is obtained which extends from the beta-1 into the alpha-2 region, demonstrating a gradient. In old serum containing totally activated C3 a single precipitin line in the alpha-2 region is obtained. Also reacts with the fragments C3b, C3bi and smaller fragments, since they all carry antigenic determinants of the C3c domain. Does not react with any other proteins component of canine serum or plasma.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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